Edema thickness was measured and skin lesions were analyzed by planimetry and histology. Swiss mice were treated with cashew juice by gavage. Those were evaluated in murine models of xylene-induced ear edema and wound excision. Juices from ripe and immature cashew apples were analyzed for antioxidant, anti-inflammatory, and wound-healing properties.
Thereby, this study evaluated the antioxidant capacity, anti-inflammatory, and wound-healing activities of cashew apple juice. In spite of being well known for its important antioxidant properties, the cashew apple has not been thoroughly investigated for its therapeutic potential. No IgE-binding peptides remained after 5 kDa filtration of the concentrate.Īnti-inflammatory and wound healing potential of cashew apple juice ( Anacardium occidentale L.) in miceĭa Silveira Vasconcelos, Mirele Gomes-Rochette, Neuza F de Oliveira, Maria LiduÃna M Nunes-Pinheiro, Diana Célia S Tomé, Adriana R Maia de Sousa, Francisco Yuri Pinheiro, Francisco Geraldo M Moura, Carlos Farley H Miranda, Maria Raquel A Mota, Erika FreitasĬashew apple is a tropical pseudofruit consumed as juice due to its excellent nutritional and sensory properties.
The cashew apple juice concentrate used in these studies contains proteins with IgE-reactive epitopes, including cashew nut legumin and vicilin. Neither IgE from cashew nut allergic sera nor the monoclonal antibodies bound any peptides in 5 kDa filtered cashew apple juice concentrate. Using monoclonal antibodies specific for cashew nut allergens, the concentrate was found to contain Ana o 1 (vicilin) and Ana o 2 (legumin). For some serum samples, IgE reactivity could be inhibited by preincubation of the serum with cashew nut extract, suggesting the presence of cashew nut-related allergens. Serum IgE of individuals allergic to cashew nut bound proteins in the cashew apple juice concentrate extract. To determine if cashew apple juice contains cashew nut allergens, immunoblotting was performed using a cashew apple juice 6X concentrate that was extracted and further concentrated through dialysis, lyophilization, and resuspension. Cashew nut allergy is the second most commonly reported tree nut allergy in the United States. The juice of the cashew apple is obtained by pressing the fleshy peduncle or receptacle, which forms a rounded apple that sits above the true fruit, the cashew nut. Immunoglobulin E-reactive proteins in cashew ( Anacardium occidentale) apple juice concentrate.Ĭomstock, Sarah S Robotham, Jason M Tawde, Pallavi Kshirsagar, Harshal Sathe, Shridhar K Roux, Kenneth H Teuber, Suzanne SĬashew apple juice has the potential to be a natural source of vitamin C and sugar in processed foods.
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